Life-Threatening Overt Small Bowel Bleeding From Jejunal Crohn’s Disease

Bleeding from the small bowel is relatively uncommon, and when suspected, its diagnosis can be challenging. It often requires additional, and sometimes multiple, endoscopic techniques to accurately identify the source. Jejunal Crohn's disease (CD) is rare and carries a higher risk of complications compared to other forms of CD. Severe anemia (hemoglobin <10) at the time of CD diagnosis is also unusual. We present a case of a 23-year-old female with obscure gastrointestinal bleeding and life-threatening anemia, who was ultimately diagnosed with jejunal Crohn's disease. This case highlights the intersection of three rare findings: small bowel bleeding, jejunal CD, and severe anemia at presentation.