Serum Proteomic Profiling Uncovers LGALS3BP as a Potential Biomarker for Idiopathic Pulmonary Arterial Hypertension
Integrated proteomic profiling and clinical validation provide the first evidence of elevated serum LGALS3BP in IPAH, indicating its putative role in pathogenesis and translational medicine.
Authors
- Dandan Chen (ORCID: https://orcid.org/0000-0003-0187-5936)
- Wenzhi Pan (ORCID: https://orcid.org/0000-0002-0530-261X)
- Lihua Guan (ORCID: https://orcid.org/0000-0001-5507-2480)
- Qi Jin (ORCID: https://orcid.org/0000-0003-3307-3663)
- Daxin Zhou (ORCID: https://orcid.org/0009-0007-9814-3630)
- Yuan Zhang (ORCID: https://orcid.org/0000-0001-5538-1478)
- Peng Wang (ORCID: https://orcid.org/0000-0002-3825-6365)
- Mingfei Li (ORCID: https://orcid.org/0000-0003-4040-3392)
- Junbo Ge (ORCID: https://orcid.org/0000-0002-9360-7332)
- Shasha Chen
- Dan Tian (ORCID: https://orcid.org/0000-0002-8511-1054)
Institutions
- Sun Yat-sen University (CN)
- Fudan University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- The Clinical Respiratory Journal
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1111/crj.70138
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Fudan University
- Science and Technology Commission of Shanghai Municipality