Effect of Bariatric Surgery on the Pharmacokinetics of Codeine, Oxycodone and Tramadol—A Case Series

From a pharmacokinetic point of view, we found no evidence that particular follow-up procedures should be needed for codeine, oxycodone and tramadol in patients undergoing bariatric surgery and continuing drug treatment. However, as always, doses should be adjusted based on clinical effect and the occurrence of adverse drug reactions.

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Publication Details

Journal
Basic & Clinical Pharmacology & Toxicology
Published
2025-11-27
DOI
https://doi.org/10.1111/bcpt.70149
Primary Topic
Veterinary Pharmacology and Anesthesia
Type
article
Field-Weighted Citation Impact
0.00

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article

Effect of Bariatric Surgery on the Pharmacokinetics of Codeine, Oxycodone and Tramadol—A Case Series

Hege‐Merete Krabseth, Olav Spigset, Magnus Strømmen, Arne Helland
Basic & Clinical Pharmacology & Toxicology
Veterinary Pharmacology and Anesthesia
article

Effect of Bariatric Surgery on the Pharmacokinetics of Codeine, Oxycodone and Tramadol—A Case Series

Hege‐Merete Krabseth, Olav Spigset, Magnus Strømmen, Arne Helland
article en

Abstract

From a pharmacokinetic point of view, we found no evidence that particular follow-up procedures should be needed for codeine, oxycodone and tramadol in patients undergoing bariatric surgery and continuing drug treatment. However, as always, doses should be adjusted based on clinical effect and the occurrence of adverse drug reactions.

Basic & Clinical Pharmacology & ToxicologyVol. 137(6)
Norwegian University of Science and Technology (NO), St Olav's University Hospital (NO)
Norges Teknisk-Naturvitenskapelige Universitet, Universitätsklinikum Tübingen, Faculty of Medicine and Health, University of Sydney
Openalex Percentile: Top 58%
Veterinary Pharmacology and Anesthesia
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