Controlling interactions between peptide-heme and G-quadruplex DNA using Fe-bound NH <sub>3</sub> and H <sub>2</sub> O ligands
This work provides the first spectroscopic evidence for binding of Fe-bound NH 3 to a G-quartet in a peptide-heme/G4 complex. Thermodynamic analysis shows that the interaction between heme and the G-quartet is highly sensitive to the NH 3 ligand.
Authors
- Xin Chang (ORCID: https://orcid.org/0000-0002-2079-0834)
- Hulin Tai (ORCID: https://orcid.org/0000-0003-0844-1022)
- Ze Sun (ORCID: https://orcid.org/0000-0002-1436-9832)
- Jing Liu (ORCID: https://orcid.org/0000-0001-5588-3865)
- Jinyang Feng
Institutions
- Yanbian University (CN)
Publication Details
- Journal
- Inorganic Chemistry Frontiers
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1039/d5qi02103k
- Primary Topic
- DNA and Nucleic Acid Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00