Differential impact of per- and polyfluoroalkyl substances exposure on hypertension risk by kidney function and metabolic status
PFAS exposure is associated with an increased risk of hypertension, particularly among those in the higher eGFR range and favorable metabolic profiles. These findings highlight the need to consider related disease phenotypes when assessing PFAS-associated cardiovascular toxicity and emphasize the importance of exposure mitigation in the healthy general population.
Authors
- Yaerim Kim (ORCID: https://orcid.org/0000-0003-1596-1528)
- Jin Hyuk Paek (ORCID: https://orcid.org/0000-0001-8875-1260)
- Seungyeup Han
- Gowoon Lee (ORCID: https://orcid.org/0000-0002-5431-6532)
- Inae Lee (ORCID: https://orcid.org/0000-0002-8031-2105)
- Jeonghwan Lee
- Chun Soo Lim (ORCID: https://orcid.org/0000-0001-9123-6542)
- Younglim Kho
- Jung Pyo Lee (ORCID: https://orcid.org/0000-0002-4714-1260)
Institutions
- Korea National University of Transportation (KR)
- Seoul National University (KR)
- Eulji University (KR)
- New Generation University College (ET)
- SNUH SMG-SNU Boramae Medical Center (KR)
- National University College (PR)
- Keimyung University (KR)
Publication Details
- Journal
- Environment International
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1016/j.envint.2025.109930
- Citations
- 1
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 0.86