Associations between sex hormones and obesity-related indicators: results from the NHANES and Mendelian randomization study
Sex hormones show sex-specific associations with obesity. Testosterone is protective against obesity in males, whereas female hyperandrogenism elevates the risk of obesity, particularly central obesity. These results offer novel perspectives for obesity-related health interventions.
Authors
- Shengjie Cui (ORCID: https://orcid.org/0000-0003-0330-1530)
- Xingqiong Meng (ORCID: https://orcid.org/0000-0001-8935-358X)
- Yanqiu Huang (ORCID: https://orcid.org/0009-0006-9317-2283)
- Yong Yuan (ORCID: https://orcid.org/0000-0002-1342-2654)
- Feng Xu (ORCID: https://orcid.org/0000-0002-6944-3075)
- Yingqi Hou
- Wentao Shi (ORCID: https://orcid.org/0009-0007-7970-8712)
Institutions
- Shanghai Jiao Tong University (CN)
- Peking University (CN)
- Shanghai Ninth People's Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Changchun University of Chinese Medicine (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Central Hospital of Putuo District (CN)
- Peking University Third Hospital (CN)
- Shanghai Zhabei District Shibei Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s40001-025-03470-x
- Citations
- 1
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 1.29