Early real-life experience on Zilucoplan for generalized myasthenia gravis: ZILU25 multicenter observational study
Zilucoplan was well-tolerated and effective in most patients with AChR-positive gMG. A clinical meaningful effect was reported since the first week and was sustained after 24 weeks. Further studies are needed to confirm these preliminary real-life data.
Authors
- Raffaele Iorio (ORCID: https://orcid.org/0000-0003-1599-7096)
- Francesco Tuccillo
- Luca Codeluppi
- Elena Rossini (ORCID: https://orcid.org/0009-0002-7862-6743)
- Claudia Vinciguerra (ORCID: https://orcid.org/0000-0002-7646-7622)
- Fiammetta Biasini (ORCID: https://orcid.org/0000-0002-2402-6569)
- Paolo Emilio Alboini (ORCID: https://orcid.org/0000-0002-9193-8816)
- Paolo Alonge (ORCID: https://orcid.org/0009-0001-3627-8974)
- Rita Frangiamore
- Carlo Antozzi (ORCID: https://orcid.org/0000-0001-9270-5224)
- Laura Fionda (ORCID: https://orcid.org/0000-0002-8813-2272)
- Alvino Bisecco (ORCID: https://orcid.org/0000-0002-7202-4445)
- Fiammetta Vanoli (ORCID: https://orcid.org/0000-0002-9081-6462)
- Silvia Bonanno (ORCID: https://orcid.org/0000-0002-8823-6821)
- Martina Verza
- Francesco Saccà (ORCID: https://orcid.org/0000-0002-1323-6317)
- Stefania Morino
- Filippo Brighina (ORCID: https://orcid.org/0000-0001-5875-3126)
- Valentina Damato (ORCID: https://orcid.org/0000-0003-1740-4522)
- Lucía Florio (ORCID: https://orcid.org/0000-0002-9608-2666)
- Giulia D’Alvano
- Francesco Habetswallner
- Melania Guida (ORCID: https://orcid.org/0000-0003-1968-5874)
- Carmen Erra (ORCID: https://orcid.org/0000-0002-8001-0836)
- Sofia Helena Valente de Lemos‐Marini (ORCID: https://orcid.org/0000-0002-8289-5703)
- Lorenzo Maggi (ORCID: https://orcid.org/0000-0002-0932-5173)
- Vincenzo Di Stefano (ORCID: https://orcid.org/0000-0001-9805-1655)
- Michelangelo Maestri Tassoni
- Nicasio Rini
- Alessio Sarnataro (ORCID: https://orcid.org/0009-0008-5042-4799)
- Alessia Pugliese (ORCID: https://orcid.org/0009-0002-9303-9299)
- Martina Marini
- Liliana Bevilacqua
- Pietro Luppino
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Messina (IT)
- University of Salerno (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Casa Sollievo della Sofferenza (IT)
- Agostino Gemelli University Polyclinic (IT)
- Ospedale Antonio Cardarelli (IT)
- Azienda Sanitaria Unità Locale di Reggio Emilia (IT)
- CTO Andrea Alesini (IT)
- Federico II University Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Fondazione IRCCS Istituto Neurologico Carlo Besta (IT)
- Azienda Ospedaliera Universitaria Pisana (IT)
- University of Florence (IT)
- Sapienza University of Rome (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Journal of the Neurological Sciences
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1016/j.jns.2025.125671
- Citations
- 7
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 9.72