Light-operated microfluidic system for the automated separation and analysis of biomarkers from complex biofluids by an on-chip chemically-modified nanopillars array

The development of this automated platform marks a substantial advancement in microfluidic analytical systems, facilitating the transition toward miniaturized, high-precision, and scalable biomedical technologies. Moreover, this system is particularly advantageous for bioanalytical applications, including point-of-care diagnostics, high-throughput screening, proteomics analysis, biomolecules separation and pre-concentration, sample pre-treatment and biomolecules depletion, personalized medicine, and environmental monitoring.