Abnormal functional integration and effective connectivity in striatal-cortical networks with neurotransmitter system correlates in migraine without aura: A resting-state fMRI study
MWoA involves disrupted functional integration and bidirectional subcortical-cortical connectivity during interictal periods, associated with headache severity and neurotransmitter system imbalances. These findings highlight network-level pathophysiology and neurochemical dysregulation underlying migraine.
Authors
- Ling Zhao (ORCID: https://orcid.org/0000-0002-4017-8167)
- Xixiu Ni (ORCID: https://orcid.org/0000-0001-7359-6173)
- Xiao Wang (ORCID: https://orcid.org/0000-0001-6395-706X)
- Linglin Dong
- Mingsheng Sun
- Chao-Rong Xie (ORCID: https://orcid.org/0000-0001-9644-931X)
- Qiang Zhang (ORCID: https://orcid.org/0000-0002-4746-0392)
- Xu Ouyang (ORCID: https://orcid.org/0000-0003-2852-5733)
- Qinyi Yan
- Qixuan Fu (ORCID: https://orcid.org/0009-0009-6238-9991)
- Zhiyang Zhang (ORCID: https://orcid.org/0009-0004-4057-7098)
Institutions
- University of Electronic Science and Technology of China (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-11-24
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111653
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00