The role of CSTF2 in gastric cancer: implications for therapy
CSTF2 promotes gastric cancer progression by post-transcriptionally stabilizing TGM2 mRNA, and its overexpression is closely related to poor prognosis. The elucidated CSTF2-TGM2 regulatory axis may offer a promising and innovative therapeutic target for gastric carcinoma treatment.
Authors
- Xiaoqi Shi
- Zhiguo Cao (ORCID: https://orcid.org/0000-0002-9223-1863)
- Changjun Yu (ORCID: https://orcid.org/0000-0002-2566-671X)
- Weiwei Xu (ORCID: https://orcid.org/0000-0001-8310-2632)
- Wenhao Liu (ORCID: https://orcid.org/0000-0002-2243-8391)
- Changyu Chen (ORCID: https://orcid.org/0000-0001-8888-1161)
- Feng Liang (ORCID: https://orcid.org/0000-0002-8985-834X)
- Jie Ning (ORCID: https://orcid.org/0000-0002-2063-7696)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Lu'an First People's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s40001-025-03570-8
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00