Evaluation of PTX/Mo <sub>2</sub> CTx-MXene@Fuc surface-engineered nanosheets in targeted combination therapy for triple-negative breast cancer
The findings indicate that PTX/Mo<sub>2</sub>CTx-MXene@Fuc nanosheets function as a multifunctional nanoplatform combining chemo-, photothermal-, and photodynamic-therapy mechanisms. Their selective cytotoxicity, ROS-mediated apoptosis, and anti-angiogenic activity highlight their strong potential for future targeted cancer therapy applications.
Authors
- Ayça Tunçel (ORCID: https://orcid.org/0000-0003-0699-3309)
- Derya Özel (ORCID: https://orcid.org/0000-0003-0596-5293)
- Cumhur Gökhan Ünlü (ORCID: https://orcid.org/0000-0003-2554-5886)
- Ersan Harputlu (ORCID: https://orcid.org/0000-0002-2140-9070)
- Buse Sert (ORCID: https://orcid.org/0000-0003-0565-775X)
- Fatma Yurt (ORCID: https://orcid.org/0000-0002-9394-6908)
- Kasım Ocakoğlu (ORCID: https://orcid.org/0000-0003-2807-0425)
- Gül Kaya (ORCID: https://orcid.org/0000-0003-3810-9872)
Institutions
- Ege University (TR)
- Tarsus University (TR)
- Institute of Natural Science (KP)
- Pamukkale University (TR)
Publication Details
- Journal
- Nanomedicine
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1080/17435889.2025.2595120
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00