Old but gold: ILC-induced T-cell senescence prevents GVHD
without simultaneous increases in recombination events.Off-target events were assessed in K562 cells using genome-wide, unbiased identification of DSBs enabled by sequencing, 6 which revealed minimal off-target activity at sites with 3 or more mismatches.
Authors
- Sophia Chen (ORCID: https://orcid.org/0000-0001-6059-0661)
Institutions
- City Of Hope National Medical Center (US)
Publication Details
- Journal
- Blood
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1182/blood.2025030805
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00