The transcription factor CUX1 exerts opposing roles in human and mouse adipocyte differentiation
The transcription factor CUX1 regulates adipocyte differentiation in opposite directions in humans and mice, emphasizing the need for species-specific models in metabolic disease research.
Authors
- David J. Steger (ORCID: https://orcid.org/0000-0003-1610-7024)
- Lin Liu (ORCID: https://orcid.org/0000-0002-9087-1146)
- Ryan Calhoun
- Patrick Seale (ORCID: https://orcid.org/0000-0001-7119-1615)
- Yang Chen (ORCID: https://orcid.org/0000-0002-2443-4087)
- Lan Cheng (ORCID: https://orcid.org/0000-0002-0572-6148)
Institutions
- University of Pennsylvania (US)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1016/j.molmet.2025.102290
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00