The impact of individualized prophylactic treatment based on pharmacokinetic parameters on the prognosis of patients with severe hemophilia A
PK-guided prophylaxis improves clinical outcomes and reduces costs, but the retrospective design and small sample size limit generalizability; further studies are needed for confirmation.
Authors
- Li Huang (ORCID: https://orcid.org/0000-0002-7899-1524)
- Xinguo Luo
- Panpan Xu (ORCID: https://orcid.org/0009-0009-2064-7200)
- Shanshan Hu (ORCID: https://orcid.org/0000-0002-9014-4168)
- Jingjing Xiang (ORCID: https://orcid.org/0000-0002-2195-9726)
- Hongwei Ye (ORCID: https://orcid.org/0000-0003-0374-5406)
- Fangquan Yu
- Xinfang Gao
Institutions
- Zhejiang Chinese Medical University (CN)
- Jinhua Academy of Agricultural Sciences (CN)
- Jinhua Central Hospital (CN)
- Jinan City People's Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Expert Review of Hematology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1080/17474086.2025.2597370
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00