Cerebral embolic protection devices in transcatheter aortic valve implantation: a systematic review and meta-analysis of randomized controlled trials
CEPD did not significantly reduce the incidence of ischemic lesions or neurocognitive decline. Current evidence does not support a statistically significant clinical benefit of CEPD use during TAVI. While trends suggest a potential reduction in stroke, larger trials are needed to establish the significance of these results.
Authors
- Zain Ul Abideen (ORCID: https://orcid.org/0000-0003-3625-008X)
- Muhammad Waseem (ORCID: https://orcid.org/0000-0002-1927-3899)
- Pawan Kumar Thada (ORCID: https://orcid.org/0000-0002-2085-8739)
- Ameer Haider Cheema (ORCID: https://orcid.org/0009-0002-2508-4370)
- Muhammad Osama (ORCID: https://orcid.org/0000-0003-0197-4264)
- Rabeya Farid
- Haseeb Javed Khan (ORCID: https://orcid.org/0009-0004-4044-114X)
- Nohela Rehman
- Sania Aimen
Institutions
- King Edward Medical University (PK)
- Allama Iqbal Medical College (PK)
- Bolan University of Medical and Health Sciences (PK)
- Hayatabad Medical Complex (PK)
- Jinnah Sindh Medical University (PK)
- Dow University of Health Sciences (PK)
- Songdo Hospital (KR)
- Southwestern Medical Center (US)
- Southerners on New Ground (US)
- Southwestern Medical Center (US)
- Institute of Medical Sciences (IN)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Expert Review of Medical Devices
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1080/17434440.2025.2595252
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00