Disproportionate impairment in diffusing capacity predicts pulmonary hypertension with an elevated pulmonary vascular resistance in COPD
These findings suggest that disproportionate reductions in DLCO predict PH with an elevated PVR in a COPD population. The FEV<sub>1</sub>/DLCO ratio should be considered in the evaluation of PH in COPD.
Authors
- Ashraf Fawzy (ORCID: https://orcid.org/0000-0002-6089-366X)
- Nadia N. Hansel (ORCID: https://orcid.org/0000-0002-8740-9751)
- Meredith C. McCormack (ORCID: https://orcid.org/0000-0003-1702-3201)
- Evan L. Brittain (ORCID: https://orcid.org/0000-0001-5843-3392)
- Paul M. Hassoun (ORCID: https://orcid.org/0000-0003-0601-4975)
- Stephen C. Mathai (ORCID: https://orcid.org/0000-0003-3188-7209)
- Robert A. Wise (ORCID: https://orcid.org/0000-0002-8353-2349)
- Catherine E. Simpson (ORCID: https://orcid.org/0000-0002-2388-5660)
- Todd M. Kolb (ORCID: https://orcid.org/0000-0003-0524-7400)
- Anna R. Hemnes (ORCID: https://orcid.org/0000-0002-2755-5845)
- Aparna Balasubramanian (ORCID: https://orcid.org/0000-0002-1854-6672)
- Nirupama Putcha (ORCID: https://orcid.org/0000-0002-0688-1836)
- Jeffrey Annis (ORCID: https://orcid.org/0000-0002-3097-4186)
- Anil Singh
Institutions
- Allegheny Health Network (US)
- Johns Hopkins University (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Thorax
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1136/thorax-2025-223921
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00