Chiral amplification of prebiotic peptide synthesis induced by chemical–physical interactions on calcite surfaces

Understanding how life substances adopted a single configuration under prebiotic conditions is central to exploring the origins of homochirality. This study shows a chiral amplification effect during prebiotic peptide synthesis on calcite surfaces, driven by the synergy between chemical synthesis and physical adsorption. This chemical-physical coupling mechanism offers a unique and promising strategy for promoting the emergence of homochirality.

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Publication Details

Journal
Chemical Communications
Published
2025-11-27
DOI
https://doi.org/10.1039/d5cc06016h
Primary Topic
Origins and Evolution of Life
Type
article
Field-Weighted Citation Impact
0.00
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article

Chiral amplification of prebiotic peptide synthesis induced by chemical–physical interactions on calcite surfaces

Shichao Yu, Jianxi Ying, Xiaofan Guo, Xinyu Zheng et al.
Chemical Communications
Origins and Evolution of Life
article

Chiral amplification of prebiotic peptide synthesis induced by chemical–physical interactions on calcite surfaces

Shichao Yu, Jianxi Ying, Xiaofan Guo, Xinyu Zheng, Yufen Zhao, Li Zhang
article en

Abstract

Understanding how life substances adopted a single configuration under prebiotic conditions is central to exploring the origins of homochirality. This study shows a chiral amplification effect during prebiotic peptide synthesis on calcite surfaces, driven by the synergy between chemical synthesis and physical adsorption. This chemical-physical coupling mechanism offers a unique and promising strategy for promoting the emergence of homochirality.

Chemical CommunicationsVol. 62(1)
Ningbo University (CN), Xiamen University (CN)
Openalex Percentile: Top 75%
Origins and Evolution of Life
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