Characterization of cell-type specific knockout of different elements of the endocannabinoid system in cortical glutamatergic neurons in the context of stress-induced behavioral phenotype
In conclusion, genetic manipulation of the endocannabinoid system in cortical glutamatergic neurons did not result in persistent effects of prolonged stress exposure. Detected differences between the genotypes in the non-stressed groups points toward baseline differences that could mask or over-power the effect of stress.
Authors
- Beat Lutz (ORCID: https://orcid.org/0000-0002-1062-6889)
- Margaryta Tevosian (ORCID: https://orcid.org/0000-0002-2225-682X)
- Andrea Conrad
- Alex F. Brown (ORCID: https://orcid.org/0009-0005-2808-2612)
- Ermelinda Lomazzo
- Christina Schneider
Institutions
- Johannes Gutenberg University Mainz (DE)
- Leibniz Institute for Resilience Research (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Hasselt University (BE)
Publication Details
- Journal
- Journal of Cannabis Research
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s42238-025-00368-7
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00