A switchable reductive cyclization of <i>o</i> -alkyl nitroarenes: divergent synthesis of heterocycles

This metal-free protocol enables the rapid and highly selective conversion of ortho -alkyl nitroaromatics into diverse heterocycles—including thiophenes, quinolines, and N -hydroxyindoles—in moderate to good yields.

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Publication Details

Journal
Green Chemistry
Published
2025-11-27
DOI
https://doi.org/10.1039/d5gc05521k
Primary Topic
Nanomaterials for catalytic reactions
Type
article
Field-Weighted Citation Impact
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article

A switchable reductive cyclization of o -alkyl nitroarenes: divergent synthesis of heterocycles

Hangyu Zhou, Meiqi Zhu, Zhengjun Wang, Dingyi Wang et al.
Green Chemistry
Nanomaterials for catalytic reactions
article

A switchable reductive cyclization of o -alkyl nitroarenes: divergent synthesis of heterocycles

Hangyu Zhou, Meiqi Zhu, Zhengjun Wang, Dingyi Wang, Yang Su, Yikun Chen
article en

Abstract

This metal-free protocol enables the rapid and highly selective conversion of ortho -alkyl nitroaromatics into diverse heterocycles—including thiophenes, quinolines, and N -hydroxyindoles—in moderate to good yields.

Green ChemistryVol. 28(2)
Zhejiang Normal University (CN), Wenzhou University (CN), Humanwell Healthcare Group (China) (CN), Nanjing University (CN), Northeastern University (CN)
Openalex Percentile: Top 72%
Nanomaterials for catalytic reactions
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