Evaluation of Microbiological and Neuroimaging Diagnostic Modalities in Tuberculous Meningitis in Children: A Prospective Observational Study from Rural India
Neuroimaging demonstrated the highest sensitivity for TBM diagnosis in children. While CBNAAT provided definitive diagnosis with high specificity, its sensitivity remained limited. A multimodal diagnostic approach incorporating clinical assessment and CSF analysis including ADA, CBNAAT, and neuroimaging is essential for optimal diagnostic accuracy in pediatric TBM.
Authors
- Himanshu Gupta (ORCID: https://orcid.org/0000-0001-9788-5703)
- Vinay Verma (ORCID: https://orcid.org/0000-0003-3924-6465)
- Ramesh Chand (ORCID: https://orcid.org/0000-0001-5231-224X)
- Muniba Alim (ORCID: https://orcid.org/0000-0001-9136-232X)
- Ganesh Kumar Verma
Institutions
- King George's Medical University (IN)
- Adesh University (IN)
Publication Details
- Journal
- Annals of African Medicine
- Published
- 2025-11-25
- DOI
- https://doi.org/10.4103/aam.aam_438_25
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00