Clinical characteristics, risk factor analysis, and outcomes of graft rejection after Descemet membrane endothelial keratoplasty

Our study suggests that the risk of rejection is higher for indications such as failed previous graft, post-cataract surgery edema, and edema postinflammatory causes, when compared to Fuchs endothelial dystrophy. Topical steroids should be continued at least up to 2 years after surgery as this is the most common time frame of the rejection episode. The majority (68%) of the rejection episodes were reversible and resulted in a favorable outcome.

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Publication Details

Journal
Indian Journal of Ophthalmology
Published
2025-11-24
DOI
https://doi.org/10.4103/ijo.ijo_722_25
Primary Topic
Corneal surgery and disorders
Type
article
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article

Clinical characteristics, risk factor analysis, and outcomes of graft rejection after Descemet membrane endothelial keratoplasty

Md Hasnat Ali, Shalini Singh, Sunita Chaurasia
Indian Journal of Ophthalmology
Corneal surgery and disorders
article

Clinical characteristics, risk factor analysis, and outcomes of graft rejection after Descemet membrane endothelial keratoplasty

Md Hasnat Ali, Shalini Singh, Sunita Chaurasia
article en

Abstract

Our study suggests that the risk of rejection is higher for indications such as failed previous graft, post-cataract surgery edema, and edema postinflammatory causes, when compared to Fuchs endothelial dystrophy. Topical steroids should be continued at least up to 2 years after surgery as this is the most common time frame of the rejection episode. The majority (68%) of the rejection episodes were reversible and resulted in a favorable outcome.

Indian Journal of OphthalmologyVol. 73(12)
L V Prasad Eye Institute (IN)
Openalex Percentile: Top 48%
Corneal surgery and disorders
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