Disparities in transplant access and outcomes after first cirrhosis decompensation in alcohol-related liver disease

This study provides the first national-level evidence from a European country showing that patients with alcohol-related cirrhosis, particularly women and those from socioeconomically disadvantaged backgrounds, experience lower access to liver transplantation and higher liver-related mortality. These findings could be important for clinicians, researchers, and health policymakers seeking to improve equity in transplant access within universal healthcare systems. While our study does not capture all clinical or psychosocial determinants of transplant eligibility, it highlights systemic disparities that could be mitigated through national referral protocols, standardised patient evaluations, and targeted support for vulnerable populations. Future work should integrate clinical data and patient-reported outcomes to further refine these observations and guide practice change.

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Publication Details

Journal
JHEP Reports
Published
2025-09-23
DOI
https://doi.org/10.1016/j.jhepr.2025.101594
Citations
1
Primary Topic
Alcohol Consumption and Health Effects
Type
article
Field-Weighted Citation Impact
1.47
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article

Disparities in transplant access and outcomes after first cirrhosis decompensation in alcohol-related liver disease

Magdalena Meszaros, Astrid Herrero, Claire Duflos, Stéphanie Faure et al.
1 citations
JHEP Reports
Alcohol Consumption and Health Effects
1.47
article

Disparities in transplant access and outcomes after first cirrhosis decompensation in alcohol-related liver disease

Magdalena Meszaros, Astrid Herrero, Claire Duflos, Stéphanie Faure, Josè Ursic‐Bedoya, Lucy Meunier, Margaux Delhomme, Charlotte De Choudens, Georges-Philippe Pageaux
article en
1 citations

Abstract

This study provides the first national-level evidence from a European country showing that patients with alcohol-related cirrhosis, particularly women and those from socioeconomically disadvantaged backgrounds, experience lower access to liver transplantation and higher liver-related mortality. These findings could be important for clinicians, researchers, and health policymakers seeking to improve equity in transplant access within universal healthcare systems. While our study does not capture all clinical or psychosocial determinants of transplant eligibility, it highlights systemic disparities that could be mitigated through national referral protocols, standardised patient evaluations, and targeted support for vulnerable populations. Future work should integrate clinical data and patient-reported outcomes to further refine these observations and guide practice change.

JHEP ReportsVol. 7(12)
Centre National de la Recherche Scientifique (FR), Université de Montpellier (FR), Centre Hospitalier Universitaire de Montpellier (FR), Institut de Génétique Moléculaire de Montpellier (FR), Hôpital Saint Eloi (FR)
Openalex Percentile: Top 13%
Alcohol Consumption and Health Effects
1.47
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Disparities in transplant access and outcomes after first cirrhosis decompensation in alcohol-related liver disease — Magdalena Meszaros, Astrid Herrero, et al. · JHEP Reports (2025) | TGRS Research Map | TGRS