Association between Y chromosome microdeletions and tes-ticular development in male pediatric patients with congenital reproductive system diseases
The prevalence of Y chromosome microdeletions is higher in male children with congenital reproductive system diseases compared to the general population, particularly in those with DSD. Hypospadias, cryptorchidism, DSD, and AZF microdeletions may be associated with delayed testicular development in these children.
Authors
- Fang Chen (ORCID: https://orcid.org/0000-0002-0242-331X)
- Yiqing Lyu (ORCID: https://orcid.org/0000-0001-8635-2952)
- Pin Li (ORCID: https://orcid.org/0000-0002-6144-0750)
- Yichen Huang (ORCID: https://orcid.org/0009-0002-7229-7782)
- Wuhen Xu
- Yan Liang (ORCID: https://orcid.org/0009-0004-3907-8902)
Institutions
- Shanghai Children's Hospital (CN)
Publication Details
- Journal
- Journal of Zhejiang University (Medical Sciences)
- Published
- 2025-11-22
- DOI
- https://doi.org/10.3724/zdxbyxb-2025-0146
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00