Eye-XAI: an explainable artificial intelligence approach for eye disease detection using symptom analysis

The early and accurate detection of eye diseases play a pivotal role in preventing vision loss and improving patients’ quality of life. It is therefore important to search for methods for improving this detection. It turns out that Artificial Intelligence (AI) has shown great promise for the detection task. However, AI models are often opaque and complex and as a result there has been a slow adoption for these models in clinical settings. In this paper Eye-XAI is introduced which provides an effective approach to the detection combining Explainable Artificial Intelligence (XAI) techniques with symptom analysis to enhance the transparency and interpretability of eye disease detection models. Our results demonstrate that Eye-XAI not only achieves high accuracy (99.11%) for eye disease detection but also provides transparent and interpretable insights into the diagnostic process. The adoption of Eye-XAI can therefore significantly enhance the early detection and management of eye diseases while empowering clinicians with a deeper understanding of its AI-based diagnostic recommendations. Furthermore, this approach promotes patient engagement by facilitating communication and trust between patients and their healthcare providers. Eye-XAI represents a major step towards the integration of XAI in ophthalmology, unlocking new possibilities for improved eye disease diagnosis and treatment.

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Publication Details

Journal
BMC Medical Informatics and Decision Making
Published
2025-11-27
DOI
https://doi.org/10.1186/s12911-025-03253-8
Citations
1
Primary Topic
Retinal Imaging and Analysis
Type
article
Field-Weighted Citation Impact
1.36
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article

Eye-XAI: an explainable artificial intelligence approach for eye disease detection using symptom analysis

Jon Rokne, Omar Jafarullah, Ahmed Al Marouf, Md Mozaharul Mottalib et al.
1 citations
BMC Medical Informatics and Decision Making
Retinal Imaging and Analysis
1.36
article

Eye-XAI: an explainable artificial intelligence approach for eye disease detection using symptom analysis

Jon Rokne, Omar Jafarullah, Ahmed Al Marouf, Md Mozaharul Mottalib, Reda Alhajj, Sadia Sobhana Ridi
article en
1 citations

Abstract

The early and accurate detection of eye diseases play a pivotal role in preventing vision loss and improving patients’ quality of life. It is therefore important to search for methods for improving this detection. It turns out that Artificial Intelligence (AI) has shown great promise for the detection task. However, AI models are often opaque and complex and as a result there has been a slow adoption for these models in clinical settings. In this paper Eye-XAI is introduced which provides an effective approach to the detection combining Explainable Artificial Intelligence (XAI) techniques with symptom analysis to enhance the transparency and interpretability of eye disease detection models. Our results demonstrate that Eye-XAI not only achieves high accuracy (99.11%) for eye disease detection but also provides transparent and interpretable insights into the diagnostic process. The adoption of Eye-XAI can therefore significantly enhance the early detection and management of eye diseases while empowering clinicians with a deeper understanding of its AI-based diagnostic recommendations. Furthermore, this approach promotes patient engagement by facilitating communication and trust between patients and their healthcare providers. Eye-XAI represents a major step towards the integration of XAI in ophthalmology, unlocking new possibilities for improved eye disease diagnosis and treatment.

BMC Medical Informatics and Decision MakingVol. 25(1)
University of Calgary (CA), University of Southern Denmark (DK), Istanbul Medipol University (TR), Bangladesh Islami University (BD), BRAC University (BD), University of Delaware (US)
Openalex Percentile: Top 14%
Retinal Imaging and Analysis
1.36
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