A feasibility study of sexual organ‐dose sparing volumetric modulated arc therapy in female low rectal cancer patients treated with three‐dimensional conformal radiation therapy
This study demonstrates that female sexual OARs can be systematically contoured and effectively spared during rectal cancer RT using SO-VMAT. Compared with 3D-CRT, SO-VMAT achieved meaningful dose reductions while maintaining target coverage. These preliminary findings support multi-institutional studies with patient-reported outcomes to validate clinical relevance and guide integration of female sexual OARs into treatment planning.
Authors
- Kristin Hsieh
- Deborah Marshall (ORCID: https://orcid.org/0000-0002-6675-7482)
- Michael Buckstein (ORCID: https://orcid.org/0000-0001-9955-5724)
- V.A. Dumane (ORCID: https://orcid.org/0000-0002-3405-0052)
- Maria Thor
- Lucy Greenwald (ORCID: https://orcid.org/0009-0000-4222-0050)
- André Williams (ORCID: https://orcid.org/0009-0002-2254-663X)
- Orly Morgan (ORCID: https://orcid.org/0000-0002-9827-7897)
- Margaret Downes (ORCID: https://orcid.org/0000-0003-2596-5151)
- Ayesha Ali (ORCID: https://orcid.org/0000-0002-7746-532X)
- R. Sheu
- Victoria Olsen
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- University of Miami (US)
- University of Toronto (CA)
- Jefferson University Hospitals (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of Applied Clinical Medical Physics
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1002/acm2.70394
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00