Evaluation of oxadiazole- <i>N</i> -phenylacetamide conjugates as VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative assessment, molecular docking, and dynamics studies
This study represents compound <b>11</b><sub><b>i,</b></sub> incorporating an oxadiazole scaffold as a promising VEGFR-2 inhibitor with potent anticancer activity.
Authors
- Rezk R. Ayyad
- Alaa Elwan (ORCID: https://orcid.org/0000-0003-4270-616X)
- İ. Çelik (ORCID: https://orcid.org/0000-0003-1182-3865)
- Helmy Sakr
- Islam I. Otify
Institutions
- Al-Azhar University (EG)
- Al-Azhar University (ID)
- Erciyes University (TR)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1080/17568919.2025.2594968
- Citations
- 2
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61