Risk elements and diagnostic indicators for asymptomatic immune checkpoint inhibitor-associated myocarditis in esophageal cancer

This article pertains to the study by Liu <i>et al</i>. Myocarditis caused by immune checkpoint inhibitors in patients with esophageal cancer is a concerning issue. This was found to be linked by increased levels of creatine kinase (CK) and CK isoenzymes, as well as older age and male gender. All these risk factors behind this phenomenon, which could be incorporated into a unified prediction model, have been briefly discussed. Several recommendations have been made to validate this prediction model for use in different clinical scenarios.

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Publication Details

Journal
World Journal of Gastroenterology
Published
2025-11-27
DOI
https://doi.org/10.3748/wjg.v31.i44.113689
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
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article

Risk elements and diagnostic indicators for asymptomatic immune checkpoint inhibitor-associated myocarditis in esophageal cancer

World Journal of Gastroenterology
Cancer Immunotherapy and Biomarkers
article

Risk elements and diagnostic indicators for asymptomatic immune checkpoint inhibitor-associated myocarditis in esophageal cancer

article en

Abstract

This article pertains to the study by Liu <i>et al</i>. Myocarditis caused by immune checkpoint inhibitors in patients with esophageal cancer is a concerning issue. This was found to be linked by increased levels of creatine kinase (CK) and CK isoenzymes, as well as older age and male gender. All these risk factors behind this phenomenon, which could be incorporated into a unified prediction model, have been briefly discussed. Several recommendations have been made to validate this prediction model for use in different clinical scenarios.

World Journal of GastroenterologyVol. 31(44)
University of Florida (US), Dhaka Medical College and Hospital (BD)
Openalex Percentile: Top 49%
Cancer Immunotherapy and Biomarkers
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