Mitochondrial connexin 43 modulates metabolic stress adaptation in glioma cell lines
Our results suggest that mt-CX43 serves as a multifunctional regulator of metabolic adaptation and stress response in glioma cell lines. Our results extend the role of mt-CX43 as an essential factor in cellular metabolic plasticity, providing new insights into the modulation of metabolic imbalances and mitochondrial dysfunction.
Authors
- Agata Zappalà (ORCID: https://orcid.org/0000-0002-0213-776X)
- Angela Maria Amorini (ORCID: https://orcid.org/0000-0003-3525-9955)
- Simona Denaro (ORCID: https://orcid.org/0000-0003-1910-0573)
- Nunzio Vicario (ORCID: https://orcid.org/0000-0001-5934-3962)
- Robert Zorec (ORCID: https://orcid.org/0000-0002-7478-3875)
- Rosalba Parenti (ORCID: https://orcid.org/0000-0002-1614-4696)
- Simona D’Aprile (ORCID: https://orcid.org/0009-0008-0810-6121)
- Maja Potokar (ORCID: https://orcid.org/0000-0001-6637-0635)
- Daniele Tibullo (ORCID: https://orcid.org/0000-0002-4416-8556)
- Jernej Jorgačevski (ORCID: https://orcid.org/0000-0003-3550-2011)
- Anna Gervasi
Institutions
- University of Ljubljana (SI)
- Università degli Studi di Enna Kore (IT)
- University of Catania (IT)
- Celica (Slovenia) (SI)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1186/s12964-025-02523-2
- Citations
- 1
- Primary Topic
- Connexins and lens biology
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- European Commission
- Javna Agencija za Raziskovalno Dejavnost RS
- Università di Catania
- Interreg