Causal association and potential mediators between obstructive sleep apnea and diabetic nephropathy: A Mendelian randomization study
Our findings suggest that genetically predicted OSA is associated with a higher risk of diabetic nephropathy. Additionally, BMI and high blood pressure are involved in the mechanism of OSA-induced diabetic nephropathy.
Authors
- Yong He (ORCID: https://orcid.org/0000-0003-1877-316X)
- Bo Yi
- Yong Wang (ORCID: https://orcid.org/0000-0001-9559-6174)
- Junxiang Wang (ORCID: https://orcid.org/0000-0003-0927-2195)
- Yun Wen
Institutions
- Southern Medical University Shenzhen Hospital (CN)
- Shenzhen Children's Hospital (CN)
Publication Details
- Journal
- Experimental Gerontology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1016/j.exger.2025.112980
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00