Elevated serum glutathione reflects endoscopic disease activity in inflammatory bowel disease
Serum GSH may serve as a systemic biomarker of endoscopic disease activity in IBD, particularly CD. While less accurate than fecal calprotectin alone, systemic oxidative stress markers strongly enhance its diagnostic performance, suggesting complementary value for disease monitoring.
Authors
- Klaas Nico Faber (ORCID: https://orcid.org/0000-0001-8893-3312)
- Harry van Goor (ORCID: https://orcid.org/0000-0002-6670-1577)
- Arno R. Bourgonje (ORCID: https://orcid.org/0000-0001-5754-3821)
- Sem Geertsema (ORCID: https://orcid.org/0000-0002-0335-5347)
- Marjan Reinders-Luinge
- Gerard D. H. Dijkstra (ORCID: https://orcid.org/0000-0003-4563-7462)
- Anneke C. Muller Kobold (ORCID: https://orcid.org/0000-0003-3457-4179)
- Karin K.R. Koerts-Steijn
- Hannah J Holstein
- Sofie de Jong
- Marian Bulthuis
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- Free Radical Biology and Medicine
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1016/j.freeradbiomed.2025.11.057
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00