Protection-free fabrication of glycopolymer-decorated electrodes for label-free electrochemical detection of pathogenic bacteria

We present a novel interfacial glycosylation method <i>via</i> biomimetic adhesion and π-π stacking without protecting groups. The resulting glycan-coated electrodes detect pathogenic bacteria down to 10<sup>2</sup> CFU mL<sup>-1</sup> in real food samples, demonstrating strong anti-interference ability and potential for food safety monitoring.

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Publication Details

Journal
The Analyst
Published
2025-11-27
DOI
https://doi.org/10.1039/d5an01136a
Primary Topic
Biosensors and Analytical Detection
Type
article
Field-Weighted Citation Impact
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Protection-free fabrication of glycopolymer-decorated electrodes for label-free electrochemical detection of pathogenic bacteria

Linheng Li, Gefei Li, Arum Han, Qing Chen et al.
The Analyst
Biosensors and Analytical Detection
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Protection-free fabrication of glycopolymer-decorated electrodes for label-free electrochemical detection of pathogenic bacteria

Linheng Li, Gefei Li, Arum Han, Qing Chen, Minghui Wang, Jing Lin, Qiaolin Guo, Wei Song
article en

Abstract

We present a novel interfacial glycosylation method <i>via</i> biomimetic adhesion and π-π stacking without protecting groups. The resulting glycan-coated electrodes detect pathogenic bacteria down to 10<sup>2</sup> CFU mL<sup>-1</sup> in real food samples, demonstrating strong anti-interference ability and potential for food safety monitoring.

The AnalystVol. 151(1)
Nanjing Forestry University (CN), Liaoning University of Traditional Chinese Medicine (CN), Affiliated Hospital of Liaoning University of Traditional Chinese Medicine (CN), Tianjin Institute of Metrological Supervision Testing (CN), Nanjing Product Quality Supervision and Inspection Institute (CN)
Openalex Percentile: Top 64%
Biosensors and Analytical Detection
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