Artificial intelligence–driven longitudinal quantification of technetium pyrophosphate uptake in cardiac amyloidosis: Correlation with multimodality imaging and outcomes
Serial <sup>99m</sup>Tc-PYP quantitation has modest correlations with other measures of disease burden including native T1. Changes in these measures were associated with risk of cardiovascular death or HF hospitalization, suggesting that the serial measurements may be clinically meaningful surrogate endpoints.
Authors
- Victor H. Jimenez‐Zepeda (ORCID: https://orcid.org/0000-0002-9294-9437)
- Nowell Mark Fine (ORCID: https://orcid.org/0000-0002-6546-6587)
- Aakash Dhananjay Shanbhag (ORCID: https://orcid.org/0000-0001-5199-3071)
- Robert J.H. Miller (ORCID: https://orcid.org/0000-0003-4676-2433)
- Damini Dey (ORCID: https://orcid.org/0000-0003-2236-6970)
- Debra Bosley
- James A. White (ORCID: https://orcid.org/0000-0002-5297-4507)
- Daniel S. Berman (ORCID: https://orcid.org/0000-0002-9176-7535)
- Piotr J. Slomka (ORCID: https://orcid.org/0000-0002-6110-938X)
- Lyndsay Litwin
- Karan Shahi
Institutions
- Cedars-Sinai Medical Center (US)
- University of Calgary (CA)
Publication Details
- Journal
- Journal of Nuclear Cardiology
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1016/j.nuclcard.2025.102573
- Citations
- 1
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.81