Peripheral Giant Cell Granuloma of the Posterior Mandible Mimicking Malignancy: A Case Report

Peripheral giant cell granuloma (PGCG) is a benign, reactive lesion of the soft tissue that arises exclusively from the gingiva or alveolar mucosa, usually secondary to local irritation or trauma. Although it is most commonly found in the anterior region, its occurrence in the posterior mandible is uncommon. We present a case involving a 48-year-old male with a gradually enlarging swelling in the right posterior mandible. Clinical, radiographic, and histopathological evaluations confirmed the diagnosis of PGCG. The lesion was surgically excised under general anesthesia, with satisfactory healing and no recurrence observed at an eight-month follow-up.

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Journal
Cureus
Published
2025-11-25
DOI
https://doi.org/10.7759/cureus.97794
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
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article

Peripheral Giant Cell Granuloma of the Posterior Mandible Mimicking Malignancy: A Case Report

Kajal Bhindora, Rajshekhar Halli, Manjula Hebbale
Cureus
Bone Tumor Diagnosis and Treatments
article

Peripheral Giant Cell Granuloma of the Posterior Mandible Mimicking Malignancy: A Case Report

Kajal Bhindora, Rajshekhar Halli, Manjula Hebbale
article en

Abstract

Peripheral giant cell granuloma (PGCG) is a benign, reactive lesion of the soft tissue that arises exclusively from the gingiva or alveolar mucosa, usually secondary to local irritation or trauma. Although it is most commonly found in the anterior region, its occurrence in the posterior mandible is uncommon. We present a case involving a 48-year-old male with a gradually enlarging swelling in the right posterior mandible. Clinical, radiographic, and histopathological evaluations confirmed the diagnosis of PGCG. The lesion was surgically excised under general anesthesia, with satisfactory healing and no recurrence observed at an eight-month follow-up.

CureusVol. 17(11)
Bharati Vidyapeeth (Deemed to be University) (IN)
Openalex Percentile: Top 48%
Bone Tumor Diagnosis and Treatments
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Peripheral Giant Cell Granuloma of the Posterior Mandible Mimicking Malignancy: A Case Report — Kajal Bhindora, Rajshekhar Halli, et al. · Cureus (2025) | TGRS Research Map | TGRS