Evaluation of a Cell-Adapted Live Attenuated African Swine Fever Virus Thai-Strain Vaccine Candidate: Highlighting Enhanced Virulence Risk in Co-Infected Pigs

The caASFV001-MA52 strain demonstrates promising immunogenicity and protection against lethal challenges, supporting its continued development as an LAV candidate. However, the observed safety concerns regarding concurrent infections emphasize the critical need for veterinary health surveillance during its future practical application.

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Publication Details

Journal
Vaccines
Published
2025-11-24
DOI
https://doi.org/10.3390/vaccines13121189
Primary Topic
Animal Disease Management and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Evaluation of a Cell-Adapted Live Attenuated African Swine Fever Virus Thai-Strain Vaccine Candidate: Highlighting Enhanced Virulence Risk in Co-Infected Pigs

Challika Kaewborisuth, Asawin Wanitchang, Jarin Kramyu, Kanjana Srisutthisamphan et al.
Vaccines
Animal Disease Management and Epidemiology
article

Evaluation of a Cell-Adapted Live Attenuated African Swine Fever Virus Thai-Strain Vaccine Candidate: Highlighting Enhanced Virulence Risk in Co-Infected Pigs

Challika Kaewborisuth, Asawin Wanitchang, Jarin Kramyu, Kanjana Srisutthisamphan, Tapanut Songkasupa, Rachod Tantilertcharoen, Theeradej Thaweerattanasinp, Nanchaya Wanasen, Payuda Hansoongnern, Papon Muangsanit, Anan Jongkaewwattana, Benjamas Liwnaree, Suphot Wattanaphansak, Nathiphat Tanwattana, Janya Saenboonrueng, Apidsada Chorpunkul, Thitawat Chanthaworn, Nattachai Suksawat, Kriangkrai Chaikhum
article en

Abstract

The caASFV001-MA52 strain demonstrates promising immunogenicity and protection against lethal challenges, supporting its continued development as an LAV candidate. However, the observed safety concerns regarding concurrent infections emphasize the critical need for veterinary health surveillance during its future practical application.

VaccinesVol. 13(12)
National Science and Technology Development Agency (TH), Chulalongkorn University (TH), Department of Livestock Development (TH)
Openalex Percentile: Top 53%
Animal Disease Management and Epidemiology
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