Myosteatosis as an independent predictor for all-cause and cardiac mortality in initial-dialysis patients: a multicenter, retrospective cohort study
Sex-specific myosteatosis thresholds (males: SMD ≤32.46 HU; females: ≤34.58 HU) derived from L3-CT independently predicted all-cause and cardiac mortality in initial-dialysis patients. The myosteatosis-based survival nomogram demonstrated moderate-to-good predictive accuracy and potential clinical utility.
Authors
- Lirong Hao (ORCID: https://orcid.org/0000-0001-9610-0724)
- Chunbo Zou
- Min Yang (ORCID: https://orcid.org/0000-0003-2444-4194)
- Chunhong Hu (ORCID: https://orcid.org/0000-0002-6343-758X)
- Jing Zheng (ORCID: https://orcid.org/0000-0003-2540-6077)
- Li Tian (ORCID: https://orcid.org/0000-0002-6022-2137)
- Yanhong Ni (ORCID: https://orcid.org/0000-0002-3890-3884)
- A-Feng Miao
- Jingjie Xiao (ORCID: https://orcid.org/0000-0002-8721-5017)
- Yao Wang (ORCID: https://orcid.org/0000-0002-4215-6092)
- John H. Zhang (ORCID: https://orcid.org/0000-0002-4319-4285)
- Yuan Li (ORCID: https://orcid.org/0000-0002-8505-9479)
- Min Li (ORCID: https://orcid.org/0000-0002-3971-9130)
- Bin Wang (ORCID: https://orcid.org/0000-0002-7166-0482)
- Jingyuan Cao
- Shi‐mei Hou
- Jian Xu (ORCID: https://orcid.org/0000-0003-2032-251X)
- Jianbing Hao (ORCID: https://orcid.org/0000-0002-6631-8842)
- Baowang Yang (ORCID: https://orcid.org/0009-0008-1894-9157)
Institutions
- Nantong University (CN)
- Covenant Health (CA)
- Southern University of Science and Technology (CN)
- Soochow University (CN)
- Zhongda Hospital Southeast University (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Northern Jiangsu People's Hospital (CN)
- Yangzhou University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fphys.2025.1687179
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jiangsu Commission of Health
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Government of Jiangsu Province
- Nanjing Medical University