The frequency of polycystic ovary syndrome in women with prediabetes compared with normoglycemic women
While the rate of PCOS was not increased in overall prediabetes group, a trend for an increased risk in IGT subgroup only was noteworthy. Positive correlation of insulin with testosterone, antral follicle count, and ovarian volume being only found in prediabetes group suggested that prediabetes might render ovaries susceptible to the PCOS-like changes. The lower AMH in prediabetes implied the toxic effects of even mild hyperglycemia on ovaries.
Authors
- Dildar Konukoğlu (ORCID: https://orcid.org/0000-0002-6095-264X)
- Doğan Yıldız (ORCID: https://orcid.org/0000-0001-9670-4173)
- Fahrettin Kelestimur (ORCID: https://orcid.org/0000-0002-2861-4683)
- Ahmet Numan Demir (ORCID: https://orcid.org/0000-0002-9997-7051)
- A.C. Tas (ORCID: https://orcid.org/0000-0003-2991-6322)
- Mustafa Sait Gönen (ORCID: https://orcid.org/0000-0002-1089-623X)
- Taner Damcı (ORCID: https://orcid.org/0000-0002-2578-058X)
- Turgut Gürer (ORCID: https://orcid.org/0000-0002-0522-3735)
- Cem Sulu (ORCID: https://orcid.org/0000-0003-2493-6068)
- Serdar Şahin (ORCID: https://orcid.org/0000-0002-6233-5418)
- Abdullah Tüten (ORCID: https://orcid.org/0000-0002-8495-6426)
- Hande Mefkure Özkaya (ORCID: https://orcid.org/0000-0001-6207-7941)
- Ipek Pervaz
Institutions
- Yeditepe University (TR)
- Istanbul University-Cerrahpaşa (TR)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fendo.2025.1722978
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Istanbul Üniversitesi-Cerrahpasa