Comparative analysis of the therapeutic effect of antibiotic bone cement on Wagner grade 3 or 4 diabetic foot ulcer in heel and non-heel areas: a retrospective cohort study
An ABC-based management strategy is effective for severe hDFU, demonstrating comparable major amputation rates to nhDFU despite more severe initial presentations. It facilitates infection control and may contribute to shortened hospitalization. Clinicians should address modifiable risk factors, particularly alcohol abuse and hypoalbuminemia, to further improve limb salvage outcomes.
Authors
- Wei An (ORCID: https://orcid.org/0000-0001-8319-2105)
- Zairong Wei (ORCID: https://orcid.org/0000-0003-1649-9929)
- Ru Ming Guan
- Jiarui Wei
- Wei Chen (ORCID: https://orcid.org/0000-0001-5451-6430)
- Li Li (ORCID: https://orcid.org/0000-0001-6301-3544)
- Jian Zhou (ORCID: https://orcid.org/0000-0002-2118-1117)
- Chengliang Deng
- Yanji Zhang (ORCID: https://orcid.org/0000-0001-7059-8974)
- Kaiyu Nie
- Shusen Chang (ORCID: https://orcid.org/0000-0002-8211-6669)
- Yang Jian
Institutions
- Zunyi Medical University (CN)
- Affiliated Hospital of Zunyi Medical College (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fendo.2025.1662731
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China