Case Report: Two cases of non-small cell lung cancer with coexistence of NTRK2 fusion and EGFR mutations

<i>NTRK2</i> fusion coexisting with <i>EGFR</i> mutations is a rare molecular characteristic of non-small cell lung cancer, accompanied by positive PD-L1 expression, and may serve as a promising biomarker for targeted therapy.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-11-26
DOI
https://doi.org/10.3389/fonc.2025.1664782
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: Two cases of non-small cell lung cancer with coexistence of NTRK2 fusion and EGFR mutations

Hengming Zhang, Yuping Zhang, Xiufeng Li
Frontiers in Oncology
Lung Cancer Treatments and Mutations
article

Case Report: Two cases of non-small cell lung cancer with coexistence of NTRK2 fusion and EGFR mutations

Hengming Zhang, Yuping Zhang, Xiufeng Li
article en

Abstract

<i>NTRK2</i> fusion coexisting with <i>EGFR</i> mutations is a rare molecular characteristic of non-small cell lung cancer, accompanied by positive PD-L1 expression, and may serve as a promising biomarker for targeted therapy.

Frontiers in OncologyVol. 15
Weifang Medical University (CN), Weifang People's Hospital (CN)
Openalex Percentile: Top 45%
Lung Cancer Treatments and Mutations
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