Clinical characteristics and treatment outcomes of cervical high-grade squamous intraepithelial lesions in women under 25 years: a retrospective cohort study
Most cervical HSIL under 25 are asymptomatic. Cytology alone is insufficient for reliable detection, HPV based screening significantly improves sensitivity. Among treatment strategies, LEEP offers the most effective histological cure rate, although potential reproductive risks warrant careful consideration in nulliparous women.
Authors
- Ke Peng (ORCID: https://orcid.org/0000-0002-6933-8160)
- Shujun Gao (ORCID: https://orcid.org/0000-0002-3217-7519)
- Yanmei Liu
Institutions
- Shanghai Medical College of Fudan University (CN)
- International Peace Maternity & Child Health Hospital (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fonc.2025.1700356
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00