Pentoxifylline vaginal gel improves sperm motility and vitality in asthenozoospermic males: A randomized, blinded, in vitro study
The PKB171 4% gel significantly improves progressive motility and preserves sperm vitality in sperm samples from asthenozoospermic males. These promising <i>in vitro</i> findings require further clinical investigation to confirm the potential benefits in infertile couples with male infertility.
Authors
- Mariona Rius (ORCID: https://orcid.org/0000-0001-7640-8588)
- Juan José Espinós (ORCID: https://orcid.org/0000-0003-4838-8940)
- Cristina Trilla (ORCID: https://orcid.org/0000-0002-5650-1790)
- L. de Navarro
Institutions
- Universitat Autònoma de Barcelona (ES)
- Instituto de Salud Carlos III (ES)
- Hospital de Sant Pau (ES)
- Prous Institute for Biomedical Research (Spain) (ES)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fphar.2025.1669045
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00