Optimized BERT-based NLP outperforms zero-shot methods for automated symptom detection in clinical practice

Our study demonstrates that modern NLP methods can reliably extract clinical symptoms from German ED free text, even under strict data protection constraints and with limited training resources. Fine-tuned models offer a precise and practical solution for integrating unstructured narratives into clinical decision-making. This work lays the methodological foundation for a new way of systematically analyzing large patient cohorts on the basis of free-text data. Beyond symptoms, this approach can be extended to extracting diagnoses, procedures, or other clinically relevant entities. Building upon this framework, we apply network-based clustering methods (in a subsequent study) to identify clinically meaningful patient subgroups and explore sex- and age-specific patterns in symptom expression.

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Publication Details

Journal
Frontiers in Digital Health
Published
2025-11-26
DOI
https://doi.org/10.3389/fdgth.2025.1623922
Citations
2
Primary Topic
Machine Learning in Healthcare
Type
article
Field-Weighted Citation Impact
4.96
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article

Optimized BERT-based NLP outperforms zero-shot methods for automated symptom detection in clinical practice

Faizan E Mustafa, Gerald Illerhaus, Markus Knott, Christian Menzel et al.
2 citations
Frontiers in Digital Health
Machine Learning in Healthcare
4.96
article

Optimized BERT-based NLP outperforms zero-shot methods for automated symptom detection in clinical practice

Faizan E Mustafa, Gerald Illerhaus, Markus Knott, Christian Menzel, Juan G. Díaz Ochoa, Natalie Layer, Martina Müller, Alexander Krohn, Tobias Schilling, Jonas Mahr
article en
2 citations

Abstract

Our study demonstrates that modern NLP methods can reliably extract clinical symptoms from German ED free text, even under strict data protection constraints and with limited training resources. Fine-tuned models offer a precise and practical solution for integrating unstructured narratives into clinical decision-making. This work lays the methodological foundation for a new way of systematically analyzing large patient cohorts on the basis of free-text data. Beyond symptoms, this approach can be extended to extracting diagnoses, procedures, or other clinically relevant entities. Building upon this framework, we apply network-based clustering methods (in a subsequent study) to identify clinically meaningful patient subgroups and explore sex- and age-specific patterns in symptom expression.

Frontiers in Digital HealthVol. 7
University Hospital Regensburg (DE), Diakonie-Klinikum Stuttgart (DE), Klinikum Stuttgart (DE)
Openalex Percentile: Top 4%
Machine Learning in Healthcare
4.96
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