Pan-cancer multi-omics characterization of calcyphosine and its revealed links to the immune microenvironment and regulatory networks in endometrial carcinoma

CAPS may act as a tumor suppressor in EC by stabilizing microtubule architecture, reprogramming cellular metabolism, and modulating immune interactions within the tumor microenvironment. These findings highlight CAPS as a promising prognostic biomarker and potential therapeutic target in EC.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-11-26
DOI
https://doi.org/10.3389/fimmu.2025.1688606
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Pan-cancer multi-omics characterization of calcyphosine and its revealed links to the immune microenvironment and regulatory networks in endometrial carcinoma

Dan Hu, Zijing Wang, Fengfeng Wang, Xuehan Bi et al.
Frontiers in Immunology
Ferroptosis and cancer prognosis
article

Pan-cancer multi-omics characterization of calcyphosine and its revealed links to the immune microenvironment and regulatory networks in endometrial carcinoma

Dan Hu, Zijing Wang, Fengfeng Wang, Xuehan Bi, Xiaolei Liang, Yongxiu Yang, Xi Chen, Ruiyue Wu
article en

Abstract

CAPS may act as a tumor suppressor in EC by stabilizing microtubule architecture, reprogramming cellular metabolism, and modulating immune interactions within the tumor microenvironment. These findings highlight CAPS as a promising prognostic biomarker and potential therapeutic target in EC.

Frontiers in ImmunologyVol. 16
Shanghai University of Traditional Chinese Medicine (CN), Traditional Chinese Medicine Hospital of Kunshan (CN), Ningxia Medical University (CN), Ningxia Medical University General Hospital (CN), Gansu Great Wall Electrical and Electronics Engineering Research Institute (CN), First Hospital of Lanzhou University (CN), Lanzhou University (CN)
Openalex Percentile: Top 45%
Ferroptosis and cancer prognosis
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