Case Report: Deep cervical lymphovenous bypass for Parkinson’s disease
DCLB was technically feasible and was followed by symptomatic improvements in this single patient. The underlying mechanism for this clinical response remains unclear and was not investigated with biomarkers in this report. While these preliminary findings are hypothesis-generating, causality cannot be inferred from an individual case. Further controlled studies incorporating neuroimaging and fluid biomarkers are needed to explore potential mechanisms.
Authors
- Meng Mao (ORCID: https://orcid.org/0000-0002-3492-6982)
- Hailong Bing (ORCID: https://orcid.org/0000-0001-9032-4428)
- Gaiqing Yang
- Qili Chu (ORCID: https://orcid.org/0000-0002-4935-3283)
- Guanyu Yang (ORCID: https://orcid.org/0000-0003-3704-1722)
- Zhengkai Li
- Yan Wang (ORCID: https://orcid.org/0000-0002-0890-8289)
- Fudi Wang (ORCID: https://orcid.org/0000-0001-8730-0003)
- Dongya Zhang (ORCID: https://orcid.org/0000-0002-9036-4590)
- Ruilei Guan
Institutions
- Zhengzhou Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fnins.2025.1707554
- Citations
- 1
- Primary Topic
- Lymphatic System and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.05