Multi−cohort validation based on coagulation-related genes for predicting prognosis of esophageal squamous cell carcinoma
We constructed and validated a robust CRGs signature. Moreover, as one of the model CRGs, the tumor-suppressive role of SULT1B1 in ESCC was experimentally verified <i>in vitro</i>. These results provide novel insights into enhancing the prognosis of ESCC and formulating treatment strategies.
Authors
- Weisong Zhang (ORCID: https://orcid.org/0009-0002-3694-5017)
- Jing Zhao (ORCID: https://orcid.org/0000-0001-5177-5699)
- ZhongQuan Yi
- H. Wang (ORCID: https://orcid.org/0000-0001-6321-2391)
- Xia Li (ORCID: https://orcid.org/0000-0002-9794-2648)
- Rui Wang (ORCID: https://orcid.org/0000-0001-6651-1485)
- Yanan Ji (ORCID: https://orcid.org/0000-0002-1179-0381)
- Jiawei Song (ORCID: https://orcid.org/0009-0006-7338-8917)
Institutions
- Yancheng Third People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fimmu.2025.1662599
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nantong University