Identification, biotransformation, and neuroprotective potential of the ethanol extract of Alpiniae oxyphyllae fructus in neuroinflammation-related cognitive impairment
These findings demonstrate that the ethanol extract of AOF exerted neuroprotective effects via its bioactive sesquiterpenoids, providing insights into the therapeutic potential of natural products (NPs) against neuroinflammation-related CNS disorders.
Authors
- Yamei Xie
- Yuming Ma (ORCID: https://orcid.org/0000-0003-4264-6785)
- Zirong Yi
- Dongying Qi
- Renfang Yin
- Guopeng Wang
- Xinyu Wang
- Nan Zhang
- Yang Liu (ORCID: https://orcid.org/0000-0002-5313-928X)
- Huan Liu (ORCID: https://orcid.org/0000-0002-1007-4148)
- Mengqi Hu (ORCID: https://orcid.org/0009-0009-4430-6611)
- Yuxin Chen (ORCID: https://orcid.org/0000-0001-5170-5797)
- Yanli Pan
- Lin Wang (ORCID: https://orcid.org/0000-0002-6710-2971)
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fphar.2025.1714500
- Primary Topic
- Ginger and Zingiberaceae research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Academy of Chinese Medical Sciences