Silver multilayer coating on orthopedic implant material of different alloys and surfaces significantly reduces bacterial colonization
These findings demonstrate a thorough and broad-spectrum antibacterial activity of the SML coating across diverse implant materials and surface textures. Future studies will focus on testing clinical PJI isolates in both <i>in vitro</i> and <i>in vivo models</i> to further evaluate the translational potential of the SML coating for prevention of bacterial colonization in joint arthroplasty.
Authors
- Jacobus J. Arts (ORCID: https://orcid.org/0000-0002-2947-8564)
- Jozef Dingemans (ORCID: https://orcid.org/0000-0001-8079-3087)
- Lydia T. D. Speijker
- Rainer Bargon
- Inge H. M. van Loo (ORCID: https://orcid.org/0000-0002-5960-4357)
- Paul H. M. Savelkoul (ORCID: https://orcid.org/0000-0002-1318-2734)
- Janine Fechter
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Jessa Hospital (BE)
- Department of Health (TW)
- Aesculap (United States) (US)
- Eindhoven University of Technology (NL)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fcimb.2025.1707694
- Citations
- 1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek