Association of Long‐Term Oral β‐Blocker Use With Cardiac Troponin I and B‐Type Natriuretic Peptide in Septic Myocardial Injury: A Retrospective Cohort Study
Long-term β-blocker therapy is associated with lower levels of cardiac injury biomarkers in patients with septic myocardial injury. Subgroup analyses revealed greater reductions in younger patients and those with pulmonary infections, though these findings are exploratory. However, these biochemical improvements did not translate into short-term survival benefits. Prospective trials are needed to determine whether myocardial protection translates into clinical benefit.
Authors
- Jianbiao Meng (ORCID: https://orcid.org/0000-0003-0337-2865)
- Zheng Yang (ORCID: https://orcid.org/0000-0002-6808-3848)
- Chun Yang (ORCID: https://orcid.org/0009-0002-3679-7536)
- Yunlong Zhu (ORCID: https://orcid.org/0009-0008-9883-9408)
- Fang Han (ORCID: https://orcid.org/0009-0001-1266-3149)
- Aihua Jiang (ORCID: https://orcid.org/0009-0003-2592-4971)
- Ke Cao (ORCID: https://orcid.org/0000-0002-0915-6429)
Institutions
- Zhejiang Chinese Medical University (CN)
- Tongde Hospital of Zhejiang Province (CN)
- Zhejiang Provincial People's Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- Health Science Reports
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1002/hsr2.71573
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00