Impaired serum neutralization and death in Omicron-infected critically ill patients: insights from the French SEVARVIR prospective, multicenter cohort study

These findings underscore the potential benefits of early therapeutic interventions aimed at enhancing neutralization, which may improve survival outcomes in both immunocompetent and immunocompromised critically ill COVID-19 patients.

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Publication Details

Journal
Intensive Care Medicine Experimental
Published
2025-11-26
DOI
https://doi.org/10.1186/s40635-025-00831-y
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Impaired serum neutralization and death in Omicron-infected critically ill patients: insights from the French SEVARVIR prospective, multicenter cohort study

Paul Bastard, Stéphane Pelleau, Antoine Guillon, Laura García et al.
Intensive Care Medicine Experimental
SARS-CoV-2 and COVID-19 Research
article

Impaired serum neutralization and death in Omicron-infected critically ill patients: insights from the French SEVARVIR prospective, multicenter cohort study

Paul Bastard, Stéphane Pelleau, Antoine Guillon, Laura García, Timothée Bruel, Jean‐Laurent Casanova, Isabelle Staropoli, Jean–Michel Pawlotsky, Olivier Schwartz, Michael White, Karl Stéfic, Anne Puel, Slim Fourati, Sébastien Préau, Fabrice Uhel, Pierre Bay, Nicolas de Prost, Aurélie Guigon, Aurélie Cobat
article en

Abstract

These findings underscore the potential benefits of early therapeutic interventions aimed at enhancing neutralization, which may improve survival outcomes in both immunocompetent and immunocompromised critically ill COVID-19 patients.

Intensive Care Medicine ExperimentalVol. 13(1)
Université de Tours (FR), Centre National de la Recherche Scientifique (FR), Howard Hughes Medical Institute (US), Inserm (FR), Institut Pasteur (FR), Université Paris-Est Créteil (FR), Université Paris Cité (FR), Institut Pasteur de Lille (FR), Centre Hospitalier Universitaire de Lille (FR), Institut Necker Enfants Malades (FR), Hôpital Louis-Mourier (FR), Centre Hospitalier Universitaire de Tours (FR), Assistance Publique – Hôpitaux de Paris (FR), Department of Virology (FR), Institut de Recherche Vaccinale (FR), Centre d'Etudes Supérieures de la Renaissance (FR), Hôpitaux Universitaires Henri-Mondor (FR), Université Gustave Eiffel (FR), Institut Mondor de Recherche Biomédicale (FR), Institut des Maladies Génétiques Imagine (FR), Rockefeller University (US)
Institut des maladies génétiques Imagine, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Fondation pour la Recherche Médicale, Assistance publique-Hôpitaux de Paris
Openalex Percentile: Top 57%
SARS-CoV-2 and COVID-19 Research
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