Efflux systems driving resistance and virulence across biological domains
Efflux systems are central players in both drug resistance and pathogenicity. Although the development of effective EIs remains challenging, advances in molecular detection, gene editing, and drug design hold potential for translational breakthroughs. A deeper understanding of efflux dynamics across organisms is essential to develop adjuvant therapies and reduce the clinical impact of MDR.
Authors
- Ivy Bastos Ramis (ORCID: https://orcid.org/0000-0003-2283-5087)
- Pedro Eduardo Almeida da Silva (ORCID: https://orcid.org/0000-0003-1666-1295)
- Ana Júlia Reis (ORCID: https://orcid.org/0000-0002-0317-9179)
- Daniela Fernandes Ramos (ORCID: https://orcid.org/0000-0001-6888-9553)
- Miguel Viveiros (ORCID: https://orcid.org/0000-0001-9676-6251)
- Andréa von Groll (ORCID: https://orcid.org/0000-0002-6727-372X)
Institutions
- Universidade Federal do Rio Grande (BR)
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- PeerJ
- Published
- 2025-11-26
- DOI
- https://doi.org/10.7717/peerj.20360
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00