The novel thioredoxin reductase inhibitor butaselen suppresses lung cancer by inducing oxidative stress
The TrxR/Trx inhibitor butaselen suppresses lung cancer by triggering ROS-induced apoptosis. This study provides a novel and effective regimen for treating lung cancer.
Authors
- Shengxin Zeng (ORCID: https://orcid.org/0009-0004-8660-0978)
- Lixiang Xue (ORCID: https://orcid.org/0000-0003-1507-7193)
- Jinhui Feng (ORCID: https://orcid.org/0000-0001-9320-7323)
- Yifan Chen (ORCID: https://orcid.org/0000-0002-2229-9037)
- Guangliang Qiang (ORCID: https://orcid.org/0000-0002-7809-1892)
- Shaohua Ma (ORCID: https://orcid.org/0000-0002-7399-6975)
- Guozhou Zhang (ORCID: https://orcid.org/0000-0002-4337-688X)
- Yan Sun (ORCID: https://orcid.org/0000-0002-4113-2929)
- Jin Liang
- Feng Wei (ORCID: https://orcid.org/0000-0001-6080-3938)
- Fengling Hu (ORCID: https://orcid.org/0000-0001-6924-2962)
- Huihui Zeng (ORCID: https://orcid.org/0000-0002-7945-6988)
Institutions
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Genetic Resources Center (JP)
- United States Bone and Joint Initiative (US)
- Spinal Research (GB)
- Peking University Third Hospital (CN)
- Ministry of Education (ET)
Publication Details
- Journal
- Redox Report
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1080/13510002.2025.2588086
- Citations
- 1
- Primary Topic
- Redox biology and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.81